RB Salzburg v Borussia Dortmund
RB Salzburg: Daka (6/0 f)
Borussia Dortmund: Akanji (5/0 d), Sancho (6/0 m), Kagawa (18/5 m), Yarmolenko (16/3 f)

Dynamo Kiev v Lazio
Dynamo Kiev: Harmash (18/2 m), Verbič (4/1 m), Bushchan (6/0 g), Sydorchuk (9/0 m)
Lazio: Strakosha (28/0 gk), Radu (26/0 d), Marusić (23/3 d), Luis Alberto (27/7 m), Milinković-Savić (26/9 m)(wszyscy niepewni)

Zenit v RB Leipzig
Zenit: Kuzyaev (20/4 m, niepewny), Mammana (16/0 d)
RB Leipzig: Laimer (18/0 m), Kampl (20/1 m)(obaj niepewni), Halstenberg (15/2 d), Lookman (5/1 f)

Athletic Bilbao v Olympique Marseille
Athletic Bilbao: Íñigo Martínez (7/0 d), Balenziaga (12/0 d), San José (18/1 m), Raúl García (27/7 m), Muniain (6/1 f)
Olympique Marseille: Sertic (4/0 m)

Lyon v CSKA Moscow
Lyon: Rafael (15/1 d), Nabil Fekir (24/16 f)
CSKA Moscow: Viktor Vasin (16/2 d), Mario Fernandes (19/0 d)

Arsenal v AC Milan
Arsenal: Pierre-Emerick Aubameyang (5/3 f), Alexandre Lacazette (26/9 f)
AC Milan: Davide Calabria (15/1 d), Ignazio Abate (13/0 d), Andrea Conti (2/0 d)