Legenda:
4/0 – liczba meczów/goli w meczach drużyny
d – defender – obrońca
m – midfielder – pomocnik
f – forward – napastnik
gk – goalkeeper – bramkarz

Slavia Praha v Racing Genk
Slavia Praha: Sykora (12/1 m), Mesanovic (5/0 f), Tecl (9/3 f), Matoušek (7/0 m)
Racing Genk: Uronen (19/1 d), Lucumi (7/0 d), Berge (18/0 m)

FK Krasnodar v Bayer Leverkusen
FK Krasnodar: Gazinskiy (16/1 m), Ramirez (14/0 d), Mamaev (10/3 m)
Bayer Leverkusen: L. Bender (14/1 m)

Lazio v Sevilla FC
Lazio: Luis Alberto (17/1 m), Immobile (22/11 f)(obaj niepewni), Milinkovic-Savic (21/3 m), Wallace (13/0 d), Lukaku (7/0 d)
Sevilla FC: Wöber (2/0 d), Aleix Vidal (7/0 d), Nolito (3/0 f), Gonalons (3/0 m)

Club Brugge v RB Salzburg
Club Brugge: Mitrovic (12/0 d), Vlietinck (7/0 d), Luan Peres (3/0 d), Vossen (6/4 f), Groeneveld (11/4 f)
RB Salzburg: Van der Werff (4/0 d), Todorović (9/0 d)

Stade Rennais v Real Betis
Stade Rennais: Bourigeaud (22/4 m, niepewny), Siebatcheu (15/3 f), Baal (1/0 d), A. Diallo (6/0 g), Johansson (10/1 m), Lea Siliki (16/0 m), Doumbia (1/0 d)
Real Betis: Bartra (21/1 d), Francis Guerrero (17/0 m), Cristian Tello (16/2 f)

BATE Borisov v Arsenal
BATE Borisov: brak
Arsenal: Mesut Özil (14/3 m), Aaron Ramsey (22/2 m), Sokratis Papastathopoulos (16/0 d), Hector Bellerin (19/0 d), Rob Holding (10/0 d), Danny Welbeck (8/1 f)

Olympiakos Pireus v Dynamo Kiev
Olympiakos Pireus: Elabdellaoui (17/2 d)
Dynamo Kiev: Kadar (14/0 d, niepewny), Vitor Bueno (2/0 m)

FC Zurich v SSC Napoli
FC Zurich: Pa Modou (15/1 d), Ruegg (13/0 m), Aliu (2/0 m)
SSC Napoli: Mário Rui (16/1 d), Verdi (10/2 f)

Malmo FF v Chelsea FC
Malmo FF: Franz Brorsson (23/0 d)
Chelsea FC: Marcos Alonso (25/1 d), Ruben Loftus-Cheek (12/3 m), Gary Cahill (1/0 d)

Celtic FC v Valencia CF
Celtic FC: Filip Benković (16/2 d), Tom Rogić (15/3 m), Kieran Tierney (14/0 d), Olivier Ntcham (14/3 m), Leigh Griffiths (11/2 f), Anthony Ralston (3/1 d), Eboue Kouassi (2/0 m), Daniel Arzani (1/0 m)
Valencia CF: Roncaglia (1/0 d), Jose Gaya (20/1 d), Gabriel Paulista (19/0 d), Santi Mina (17/2 f), Rodrigo (21/4 f)